A Retrospective Study to Evaluate the Real-World Effectiveness of Lorlatinib Among ROS1-Positive NSCLC Patients

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY

The purpose of this study is to learn about lorlatinib for the possible treatment of lung cancer which could not be controlled. This study is seeking participants who: * have lung cancer that could not be controlled. * have a type of gene called a ROS proto-oncogene 1. A gene is a part of your DNA that has instructions for making things your body needs to work. * have received at least 1 treatment before. All participants in this study had received lorlatinib. Lorlatinib is a tablet that is taken by mouth at home. They continued to take lorlatinib until their cancer was no longer responding. The study will look at the experiences of people receiving the study medicine. This will help to see if the study medicine is safe and effective.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients are aged 18 years or older on index date

• Patients have confirmed diagnosis of ROS1-positive NSCLC

• Patients have received at least one dose of lorlatinib between 1st April, 2018, and 30th September, 2023

Locations
Other Locations
Taiwan
Pfizer Inc
RECRUITING
Taipei
Contact Information
Primary
Pfizer CT.gov Call Center
ClinicalTrials.gov_Inquiries@pfizer.com
1-800-718-1021
Time Frame
Start Date: 2025-07-04
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 500
Treatments
Lorlatinib
Patients with ROS1(+) advanced/metastatic NSCLC had been treated with lorlatinib.
Sponsors
Leads: Pfizer

This content was sourced from clinicaltrials.gov